Developmental Biology

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Light-Sheet Microscopy for Developmental Biology

Explore developmental processes in embryos and living organisms with light-sheet microscopy. These imaging examples capture growth, morphogenesis and structural changes over time, with captions providing available information on samples, labeling and imaging conditions.

Ganglion imaged with the PhaseView Alpha3 light-sheet microscope — Ganglion imaging with the PhaseView Alpha3 Light Sheet Microscope. © 2016 PhaseView.

CUBIC-L/R transparized E11.5 mouse embryo with muscular and nervous systems — E11.5 mouse embryo transparized with CUBIC-L/R, showing the muscular system in red and the nervous system in white. Courtesy of Eglantine Heude and Frida Sanchez Garrido, Muséum national d’Histoire naturelle, France. © 2024 PhaseView.

Fifteen-hour zebrafish egg time-lapse with endothelial GFP staining — Fifteen-hour time-lapse of a zebrafish egg with endothelial GFP staining and transmitted light. Courtesy of Beatriz Novoa and Antonio Figueras, Immunology and Genomics Lab, Institute of Marine Research. © 2023 PhaseView.

Twenty-eight-hour Astyanax morpho development time-lapse — Twenty-eight-hour time-lapse of Astyanax morpho development with mCherry nuclear staining and GFP cytoplasmic staining in the head. © 2023 PhaseView.

Drosophila egg with RFP-labelled nuclei and GFP-labelled membranes — Drosophila egg with RFP nuclear staining and GFP membrane staining. Objective: 60X/1.0 NA water immersion. © 2023 PhaseView.

Zebrafish embryo at 36 hours post-fertilization with RFP and GFP staining. © 2023 PhaseView.

Working on a developmental imaging project?

Tell us about your sample, labeling and imaging goals. Whether you are following development over time or examining structural changes at a specific stage, we can help you explore an imaging approach for your experiment.

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