Neuroscience Imaging

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Light-Sheet Imaging for Neuroscience

Explore brain, retina and neuronal structures with light-sheet microscopy. These imaging examples show three-dimensional neural anatomy and activity-related labeling across intact samples, with captions providing available information on staining, objectives and acquisition conditions.

iDISCO-cleared mouse brain with c-Fos marking in the green channel. Objective: Olympus UPLFLN4X, 4X/0.28 NA/30 WD. Courtesy of Dr. Genaro Hernandez, University of Texas Southwestern, Dallas, USA.

Adult zebrafish brain imaged at 10X with the PhaseView Alpha3 microscope — Adult zebrafish brain imaged with the PhaseView Alpha3 Light Sheet Microscope at 10X/0.6 NA. Courtesy of Matthieu Simion, TEFOR Paris-Saclay. © 2021 PhaseView.

Mouse retinal whole mount with Thy1-GCaMP3 — Retinal whole mount from a mouse with Thy1-GCaMP3. Objective: Olympus XLFLUOR4X/340, 4X/0.28 NA/30 WD. Courtesy of Tamas Kovács-Öller, Szentágothai Research Centre.

Studying the brain, retina or neuronal structures?

Tell us about your sample, labeling strategy and imaging goals. If your application is different from the examples shown here, we can still help you explore a suitable imaging approach.

Studying the brain, retina or neuronal structures?

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